Publications

Philipp TM, Gong W, Köhnlein K, Ohse VA, Müller FI, Priebs J, Steinbrenner H, Klotz LO. (2022) SEMO-1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro-aging factor conferring selective stress resistance.External link Biofactors 48(3):699-706

Suo M, Rommelfanger MK, Chen Y, Amro EM, Han B, Chen Z, Szafranski K, Chakkarapan SR, Boehm BO, MacLean AL, Rudolph KL. (2022) Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.External link Blood 139(17):2653-2665

Stojilijkovic MR, Schmeer C, Witte OW. (2022) Pharmacological depletion of microglia leads to a dose-dependent reduction in inflammation and senescence in the aged murine brain.External link Neuroscience 488:1-9

Morales-Prieto DM, Murrieta-Coxca JM, Stokilijkovic M, Diezel C, Streicher PE, Henao-Restrepo JA, Röstel F, Lindner J, Witte OW, Weis S, Schmeer C, Marz M. (2022) Small extracellular vesicles from peripheral blood of aged mice pass the blood-brain barrier and induce glial cell activationExternal link. Cells 11(4):625

Ederer ML, Günther M, Best L, Lindner J, Kaleta C, Witte OW, Simon R, Frahm C. (2022) Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain. External linkCells 11(3):566

Reuter H, Perner B, Wahl F, Rohde L, Koch P, Groth M, Buder K, Englert C. (2022) Aging activates the immune system and alters the regenerative capacity in the zebrafish heart.External link Cells 11(3):345

Ullmann S, Strauß B, Tiesler F, Schneider N, Gensichen J, Brenk-Franz K. (2022) Patient characteristics as predictors of sleep disturbances in multimorbid primary care patients - A secondary analysis.External link J Psychosom Res, 153:110705

Schuetz JS, Uebelmesser S, Aprea C, Baginski R. (2022) Pension Reform Preferences in Germany: Does Information Matter?. University of Jena

Morales-Prieto DM, Murrieta-Coxca JM, Stokilijkovic M, Diezel C, Streicher PE, Henao-Restrepo JA, Röstel F, Lindner J, Witte OW, Weis S, Schmeer C, Marz M. (2022) Small extracellular vesicles from peripheral blood of aged mice pass the blood-brain barrier and induce glial cell activationExternal link. Cells 11(4):625

Schädel P, Troisi F, Czapka A, Gebert N, Pace S, Ori A, Werz O. (2021) Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice.External link FASEB J, 35(5):e21558

Wolfram T, Weidenbach LM, Adolf J, Schwarz M, Schädel P, Gollowitzer A, Werz O, Koeberle A, Kipp AP, Koeberle SC. (2021) The trace element selenium is important for redox signaling in phorbol ester-differentiated THP-1 macrophagesExternal link. Int J Mol Sci 22(20):11060

Schmidt M, Weidemann A, Poser C, Bigot A, von Maltzahn J. (2021) Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentia-tion and Regeneration of Skeletal MuscleExternal link. Front Cell Dev Biol 2021, 9:721543

Coronel L, Riege K, Schwab K, Förste S, Häckes D, Semerau L, Bernhart SH, Siebert R, Hoffmann S, Fischer M. (2021) Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stressExternal link. Nucleic Acids Res, 49(13):7437-56

Wandt VK, Winkelbeiner N, Lossow K, Kopp JF, Schwarz M, Alker W, Nicolai M, Simon L, Dietzele C, Zimmermann S, Hertel B, Pohl G, Ebert F, Schomburg L, Haase H, Bornhorst J, Kipp AP*, Schwerdtle T*. (2021) Aging-associated effects of a long-term dietary modulation of four trace elements in miceExternal link. Redox Biol, 46:102083

Coppin E, Sundarasetty BS, Rahmig S, Blume J, Verheyden NA, Bahlmann F, Ravens S, Schubert U, Schmid J, Ludwig S, Geissler K, Guntinas-Lichius O, von Kaisenberg C, Groten T, Platz A, Naumann R, Ludwig B, Prinz I, Waskow C, Krueger A. (2021) Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7External link. Leukemia, 35:3561-3567

Deb S, Felix DA, Koch P, Deb MK, Szafranski K, Buder K, Sannai M, Groth M, Kirkpatrick J, Pietsch S, Gollowitzer A, Groß A, Riemenschneider P, Koeberle A, González-Estévez C, Rudolph KL. (2021) Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasisExternal link. EMBO Rep, 22(1):e49328

Li H, Li Y, Zhang Y, Tan B, Huang T, Xiong J, Tan X, Ermolaeva MA, Fu L. (2021) MAPK10 Expression as a Prognostic Marker of the Immunosuppressive Tumor Microenvironment in Human Hepatocellular Carcinoma.External link Front Oncol, 11:687371

Sahm A, Koch P, Horvath S, Hoffmann S. (2021) An analysis of methylome evolution in primatesExternal link. Mol Biol Evol,38(11):4700-14

Kirtay M, Sell J, Marx C, Haselmann H, Ceanga M, Zhou ZW, Rahmati V, Kirkpatrick J, Buder K, Grigaravicius P, Ori A, Geis C, Wang ZQ. (2021) ATR regulates neu-ronal activity by modulating presynaptic firingExternal link. Nat Commun, 12(1):4067

Behrendt L, Hoischen C, Kaether C. (2021) Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy.External link Neurobiol Dis, 155:105400

Tapias A, Lázaro D, Yin BK, Rasa SMM, Krepelova A, Kelmer Sacramento E, Grigaravicius P, Koch P, Kirkpatrick J, Ori A, Neri F, Wang ZQ. (2021) HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neuro-degenerationExternal link. eLife, 10:e61531

Srivastava A, Barth E, Ermolaeva MA, Guenther M, Frahm C, Marz M, Witte OW. (2021) Tissue-specific Gene Expression Changes Are Associated with Aging in MiceExternal link. Genomics Proteomics Bioinformatics, 18(4):430-42

Schwarz R, Koch P, Wilbrandt J, Hoffmann S. (2021) Locus-specific expression analy-sis of transposable elementsExternal link. Brief Bioinform, 23(1):bbab417

Hua C, Wei W, Zhang T, Xu F, Dirsch O, Homeyer A, Settmacher U, Dahmen U. (2021) Additional partial hepatectomy at the time of portal vein ligation accelerates the regeneration of the future liver remnant.External link Sci Rep, 11(1): 11740

Xu F, Tautenhahn HM, Dirsch O, Dahmen U. (2021) Modulation of Autophagy: A Novel "Rejuvenation" Strategy for the Aging LiverExternal link. Oxid Med Cell Longev, 6611126

Seidel G, Gaser C, Götz T, Günther A, Hamzei F. (2020) Accelerated brain ageing in sepsis survivors with cognitive long-term impairment.External link Eur J Neurosci, 52(10):4395-4402

Espada L, Dakhovnik A, Chaudhari P, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Döring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA. (2020) Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegansExternal link. Nat Metab, 2(11):1316-31

Xu F, Hua C, Tautenhahn HM, Dirsch O, Dahmen U. (2020) The Role of Autophagy for the Regeneration of the Aging Liver.External link Int J Mol Sci, 21(10): 3606

Lossow K*, Kopp J*, Schwarz M, Finke H, Winkelbeiner NL, Renko K, Meci X, Ott C, Alker W, Hackler J, Grune T, Schomburg L, Haase H, Schwerdtle T*, Kipp AP*. (2020) Aging affects sex- and organ-specific trace element profiles in mice. External linkAging (Albany, NY), 12:13762-13790

Zhou ZW, Kirtay M, Schneble N, Yakoub G, Ding M, Rüdiger T, Siniuk K, Lu R, Jiang YN, Li TL, Kaether C, Barzilai A, Wang ZQ. (2020) NBS1 interacts with Notch signaling in neuronal homeostasisExternal link. Nucleic Acids Res, 48(19):10924-39

Joshi G, Eberhardt AO, Lange L, Winkler R, Hoffmann S, Kosan C, Bierhoff H. (2020) Dichotomous Impact of Myc on rRNA Gene Activation and Silencing in B Cell Lymphomagenesis.External link Cancers (Basel), 12(10):E3009

Kaiser A, Schmidt M, Huber O, Frietsch JJ, Scholl S, Heidel FH, Hochhaus A, Müller JP, Ernst T. (2020) SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders.External link Leukemia, 34(8):2206-2216

Kelmer Sacramento E, Kirkpatrick JM, Mazzetto M, Baumgart M, Bartolome A, Di Sanzo S, Caterino C, Sanguanini M, Papaevgeniou N, Lefaki M, Childs D, Bagnoli S, Terzibasi Tozzini E, Di Fraia D, Romanov N, Sudmant PH, Huber W, Chondrogianni N, Vendruscolo M, Cellerino A, Ori A. (2020) Reduced proteasome activity in the aging brain results in ribosome stoichiom-etry loss and aggregationExternal link. Mol Syst Biol, 16(6):e9596

Sharifi' S, Costa HFRd, Bierhoff H. (2020) The circuitry between ribosome biogene-sis and translation in stem cell function and ageingExternal link. Mech Ageing Dev, 189:111282

Elster D, von Eyss B. (2020) Hippo Signaling in Regeneration and AgingExternal link. Mech Ageing Dev, 189:111280.

Jayavelu AK, Schnöder TM, Perner F, Herzog C, Meiler A, Krishnamoorthy G, Huber N, Mohr J, Edelmann-Stephan B, Austin R, Brandt S, Palandri F, Schrö-der N, Isermann B, Edlich F, Sinha AU, Ungelenk M, Hübner CA, Zeiser R, Rahmig S, Waskow C, Coldham I, Ernst T, Hochhaus A, Jilg S, Jost PJ, Mullal-ly A, Bullinger L, Mertens PR, Lane SW, Mann M, Heidel FH. (2020) Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasmsExternal link. Nature, 588(7836):157-63

Schnerwitzki D, Hayn C, Perner B, Englert C. (2020) Wt1 Positive dB4 Neurons in the Hindbrain Are Crucial for RespirationExternal link. Front Neurosci, 14:529487

Alic L, Papac-Milicevic N, Czamara D, Rudnick RB, Ozsvar-Kozma M, Hartmann A,
Gurbisz M, Hoermann G, Haslinger-Hutter S, Zipfel PF, Skerka C, Binder EB, Binder
CJ. (2020) A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopesExternal link. PNAS, 117(18):9942-9951

Ayalon L, Chasteen A, Diehl M, Levy B, Neupert SD, Rothermund K, Tesch-Römer C, Wahl HW. (2020) Aging in Times of the COVID-19 Pandemic: Avoiding Ageism and Fostering Intergenerational SolidarityExternal link. J Gerontol B Psychol Sci Soc Sci, 76(2):e49-e52

Ain Q, Schmeer C, Wengerodt D, Witte OW, Kretz A. (2020)  Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and NeurodegenerationExternal link. Int J Mol Sci, 21(7). pii: E2477

Kaiser A, Schmidt M, Huber O, Frietsch JJ, Scholl S, Heidel FH, Hochhaus A, Müller JP, Ernst T. SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disordersExternal link. Leukemia. 2020 34:2206-2216

Jin CJ, Baumann A, Brandt A, Engstler AJ, Nier A, Hege M, Schmeer C, Kehm R,
Höhn A, Grune T, Witte OW, Bergheim I. (2020) Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levelsExternal link. Am J Physiol Gastrointest Liver Physiol, 318(4):G736-G747

Cairns JT, Habgood A, Edwards-Pritchard RC, Joseph C, John AE, Wilkinson C, Stewart ID, Leslie J, Blaxall BC, Susztak K, Alberti S, Nordheim A, Oakley F, Jenkins G, Tatler AL. (2020) Loss of ELK1 has differential effects on age-dependent organ fibrosis.External link Int J Biochem Cell Biol, 120:105668

Njeru SN, Kraus J, Meena JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler HA, Günes C, Rudolph KL. (2020) Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.External link Oncogene, 39(7):1445-1465

Park J, Fung HH, Rothermund K, Hess TM. (2020)  The Impact of Perceived Control and Future-Self Views on Preparing for the Old Age: Moderating Influences of Age, Culture, and ContextExternal link. J Gerontol B Psychol Sci Soc Sci, 75(5):e18-e28

Köhnlein K, Urban N, Guerrero-Gómez D, Steinbrenner H, Urbánek P, Priebs J, Koch P, Kaether C, Miranda-Vizuete A, Klotz LO. (2020) A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.External link Redox Biol, 28:101323

Fichtner M, Schuster S, Stark H. (2020) Determination of scoring functions for protein damage susceptibility.External link Biosystems, 187:104035

Jacome-Galarza CE, Percin GI, Muller JT, Mass E, Lazarov T, Eitler J, Rauner M, Yadav VK, Crozet L, Bohm M, Loyher PL, Karsenty G, Waskow C, Geissmann F.  Developmental origin, functional maintenance and genetic rescue of osteoclastsExternal link. Nature 2019, 568(7753): 541-5

Montesano A, De Felice E, Leggieri A, Palladino A, Lucini C, Scocco P, de Girolamo P, Baumgart M, D'Angelo L. Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise KillifishExternal link. J Clin Med. 2019 9(1). pii: E103.

Baudry J, Kopp JF, Boeing H, Kipp AP, Schwerdtle T, Schulze MB. (2019) Changes of trace element status during aging: results of the EPIC-Potsdam cohort studyExternal link. Eur J Nutr, 59(7):3045-3058

Behrendt L, Kurth I, Kaether C. A disease causing ATLASTIN 3 mutation af-fects multiple endoplasmic reticulum-related pathwaysExternal link. Cell Mol Life Sci 2019, 76(7):1433-45.

Mende N, Jolly A, Percin GI, Günther M, Rostovskaya M, Krishnan SM, Oostendorp RAJ, Dahl A, Anastassiadis K, Höfer T, Waskow C. Prospective isolation of non-hematopoietic cells of the niche and their differential molecular interactions with HSCsExternal link. Blood 2019, 134(15):1214-26

Kathner-Schaffert C, Karapetow L, Günther M, Rudolph M, Dahab M, Baum E, Lehmann T, Witte OW, Redecker C, Schmeer CW, Keiner S. Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline.External link Cells. 2019 8(12). pii: E1654.

Wengerodt D, Schmeer C, Witte OW, Kretz A. Amitosenescence and Pseudomitosenescence: Putative New Players in the Aging ProcessExternal link. Cells. 2019 8(12). pii: E1546.

Schmeer C, Kretz A, Wengerodt D, Stojiljkovic M, Witte OW. Dissecting Aging and Senescence-Current Concepts and Open LessonsExternal link. Cells. 2019 8(11). pii: E1446.

Ye Z, Mittag S, Schmidt M, Simm A, Horstkorte R, Huber O. Wnt Glycation Inhibits Canonical Signaling.External link Cells. 2019 8(11). pii: E1320.

Barth E, Srivastava A, Stojiljkovic M, Frahm C, Axer H, Witte OW, Marz M. Conserved aging-related signatures of senescence and inflammation in different tissues and speciesExternal link. Aging (Albany NY). 2019 11(19):8556-8572.

Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C. The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion pro-teins regulate Notch signalingExternal link. Biol Chem 2019, 294(31), 11741-50.

Cui Y, Groth S, Troutman S, Carlstedt A, Sperka T, Riecken LB, Kissil JL, Jin H, Morrison H. The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signalingExternal link. Oncogene 2019, 38(36), 6370-81

Cencioni C, Heid J, Krepelova A, Rasa SMM, Kuenne C, Guenther S, Baumgart M, Cellerino A, Neri F, Spallotta F, Gaetano C. Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal MuscleExternal link. Cells. 2019 8(10). pii: E1169.

Papaevgeniou N, Hoehn A, Tur JA, Klotz LO, Grune T, Chondrogianni N. Sugar-derived AGEs accelerate pharyngeal pumping rate and increase the lifespan of Caenorhabditis elegansExternal link. Free Radic Res. 2019 53(sup1):1056-1067.

Hernández-Arriaga A, Baumann A, Witte OW, Frahm C, Bergheim I, Camarinha-Silva A. Changes in Oral Microbial Ecology of C57BL/6 Mice at Different Ages Associated with Sampling MethodologyExternal link. Microorganisms. 2019 7(9). pii: E283.

Chin-Chan M, Cobos-Puc L, Alvarado-Cruz I, Bayar M, Ermolaeva M. Early-life Pb exposure as a potential risk factor for Alzheimer's disease: are there hazards for the Mexican population?External link J Biol Inorg Chem 2019, 24(8), 1285-303.

Perner F, Perner C, Ernst T, Heidel FH. Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant TransformationExternal link. Cells. 2019 Aug 8;8(8). pii: E854.

Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn J, Tümpel S, Rudolph KL. Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.External link Nature. 2019 572(7769):E11-E15.

Dammann P, Scherag A, Zak N, Szafranski K, Holtze S, Begall S, Burda H, Kestler HA, Hildebrandt T, Platzer M. Comment on 'Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age'External link. eLife. 2019 8. pii: e45415.

Tümpel S, Rudolph KL. Quiescence: Good and Bad of Stem Cell AgingExternal link. Trends Cell Biol. 2019 29(8):672-685.

Blanke ES, Riediger M. Reading thoughts and feelings in other people: Empathic accuracy across adulthoodExternal link. Prog Brain Res. 2019 247:305-327.

Irizar PA, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C. Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.External link Nat Commun. 2019 10(1):2459.

Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetre-an O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Mo-rioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyoka-wa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT. IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastomaExternal link. Nat Cell Biol 2019, 21(8):1003-14

Gessner G, Runge S, Koenen M, Heinemann SH, Koenen M, Haas J, Meder B, Thomas D, Katus HA, Schweizer PA. ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrierExternal link. Biochem Biophys Res Commun. 2019 512(4):845-851.

Hüttner SS, Ahrens HE, Schmidt M, Henze H, Jung MJ, Schüler SC, von Maltzahn J. Isolation and Culture of Individual Myofibers and Their Adjacent Muscle Stem Cells from Aged and Adult Skeletal MuscleExternal link. Methods Mol Biol. 2019 2045:25-36.

Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL. Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageingExternal link. Nat Cell Biol. 2019 21(6):791-792.

Cherkas A, Mondol AS, Rüger J, Urban N, Popp J, Klotz LO, Schie IW. Label-free molecular mapping and assessment of glycogen in C. elegansExternal link. Analyst. 2019 144(7):2367-2374.

Schmidt M, Schüler SC, Hüttner SS, von Eyss B, von Maltzahn J. Adult stem cells at work: regenerating skeletal muscle.External link Cell Mol Life Sci 2019, 76(13): 2559-70.

Prell T, Stubendorff B, Le TT, Gaur N, Tadić V, Rödiger A, Witte OW, Grosskreutz J. Reaction to Endoplasmic Reticulum Stress via ATF6 in Amyotrophic Lateral Sclerosis Deteriorates With Aging.External link Front Aging Neurosci. 2019 11:5.

Montesano A, Baumgart M, Avallone L, Castaldo L, Lucini C, Tozzini ET, Cellerino A, D'Angelo L, de Girolamo P. Age-related central regulation of orexin and NPY in the short-lived African killifish Nothobranchius furzeriExternal link. J Comp Neurol. 2019 527(9):1508-1526.

Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H. (2018) Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagyExternal link. Aging Cell, 17(1): e12708

Sahm A, Bens M, Henning Y, Vole C, Groth M, Schwab M, Hoffmann S, Platzer M, Szafranski K, Dammann P. (2018) Higher gene expression stability during aging in long-lived giant mole-rats than in short-lived rats. External linkAging (Albany NY), 10(12):3938-3956

Bates T, Naumann U, Hoppe B, Englert C. (2018) Kidney regeneration in fishExternal link. Int J Dev Biol, 62:419-429

Ain Q, Schmeer C, Penndorf D, Fischer M, Bondeva T, Förster M, Haenold R, Witte OW, Kretz A. (2018) Cell cycle-dependent and -independent telomere shortening accompanies murine brain agingExternal link. Aging (Albany NY), 10(11):3397-3420

Ermolaeva M, Neri F, Ori A, Rudolph KL. (2018)  Cellular and epigenetic drivers of stem cell ageingExternal link. Nat Rev Mol Cell Biol, 19(9):594-610

Dietzek M, Finn S, Karvouniari P, Zeller MA, Klingner CM, Guntinas-Lichius O, Witte OW, Axer H. (2018) In Older Patients Treated for Dizziness and Vertigo in Multimodal Rehabilitation Somatic Deficits Prevail While Anxiety Plays a Minor Role Compared to Young and Middle Aged PatientsExternal link. Front Aging Neurosci, 10:345

Job V, Sieber V, Rothermund K, Nikitin J. (2018) Age differences in implicit theories about willpower: Why older people endorse a nonlimited theory. External link Psychology and Aging, 33(6): 940-952

Müller C, Zidek LM, Ackermann T, de Jong T, Liu P, Kliche V, Zaini MA, Kortmann G, Harkema L, Verbeek DS, Tuckermann JP, von Maltzahn J, de Bruin A, Guryev V, Wang ZQ, Calkhoven CF. (2018) Reduced expression of C/EBPβ-LIP extends health and lifespan in miceExternal link. eLife, 7:e34985

Bär L, Feger M, Fajol A, Klotz LO, Zeng S, Lang F, Hocher B, Föller M. (2018) Insulin suppresses the production of fibroblast growth factor 23 (FGF23)External link. PNAS, 115(22):5804-5809

Ahrens HE, Huettemeister J, Schmidt M, Kaether C, von Maltzahn J. (2018) Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscleExternal link. Skelet Muscle, 8(1):20

Voss P, Bodner E, Rothermund K. (2018) Ageism: The relationship between age stereotypes and age discrimination. In L. Ayalon & C. Tesch-Römer (Eds.). Contemporary perspectives on ageism, (pp. 11-31)

Elster D, Tollot M, Schlegelmilch K, Ori A, Rosenwald A, Sahai E, von Eyss B. (2018) TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.External link Nat Commun, 9(1): 3115

Mayerl S, Schmidt M, Doycheva D, Darras VM, Hüttner SS, Boelen A, Visser TJ, Kaether C, Heuer H, von Maltzahn J. (2018) Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle RegenerationExternal link. Stem Cell Reports, 10(6):1959-1974

Sahm A, Bens M, Szafranski K, Holtze S, Groth M, Görlach M, Calkhoven C, Müller C, Schwab M, Kraus J, Kestler HA, Cellerino A, Burda H, Hildebrandt T, Dammann P, Platzer M. (2018) Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. External linkPLoS Genet, 14(4): e1007272

Voss P, Kornadt AE, Hess TM, Fung, HH, Rothermund, K. (2018) A world of difference? Domain-specific views on aging in China, the US, and Germany. External linkPsychology and Aging, 33(4): 595-606

Koeberle A, Henkel A, Verhoff M, Tausch L, König S, Fischer D, Kather N, Seitz S, Paul M, Jauch J, Werz O. (2018) Triterpene Acids from Frankincense and Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G.External link Molecules, 23(2). pii: E506

Kuo AH, Li C, Mattern V, Huber HF, Comuzzie A, Cox L, Schwab M, Nathanielsz PW, Clarke GD. (2018) Sex-dimorphic acceleration of pericardial, subcutaneous, and plasma lipid increase in offspring of poorly nourished baboons.External link Int J Obes (Lond), 42(5):1092-1096

Büttner R, Schulz A, Reuter M, Akula AK, Mindos T, Carlstedt A, Riecken LB, Baader SL, Bauer R, Morrison H. (2018) Inflammaging impairs peripheral nerve maintenance and regeneration.External link Aging Cell, 17(6), e12833

Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C. (2018) Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.External link Nat Commun, 9(1):327

Kan C, Ungelenk L, Lupp A, Dirsch O, Dahmen U. (2018) Ischemia-Reperfusion Injury in Aged Livers-The Energy Metabolism, Inflammatory Response, and Autophagy.External link Transplantation, 102(3):368-377

Kornadt AE, Voss P, Rothermund K. (2017) Subjective remaining lifetime and concreteness of the future as differential predictors of preparation for age-related changes.External link Eur J Ageing, 15(1):67-76

Gunes C, Avila AI, Rudolph KL. (2018) Telomeres in cancer.External link Differentiation (epub 2017), 99:41-50

Christ B, Dahmen U, Herrmann KH, König M, Reichenbach JR, Ricken T,
Schleicher J, Ole Schwen L, Vlaic S, Waschinsky N. (2017) Computational Modeling in Liver Surgery.External link Front Physiol, 8:906

Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, Hu Q, Dirsch O, Dahmen U, Zhang
C, Gewirtz DA, Fang H. (2017) Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.External link Aging Cell, 17(1)

Heid J, Cencioni C, Ripa R, Baumgart M, Atlante S, Milano G, Scopece A, Kuenne C, Guenther S, Azzimato V, Farsetti A, Rossi G, Braun T, Pompilio G, Martelli F, Zeiher AM, Cellerino A, Gaetano C, Spallotta F. (2017) Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health.External link Sci Rep, 7(1):16839

Franke K, Gaser C, Roseboom TJ, Schwab M, de Rooij SR. (2018)  Premature brain aging in humans exposed to maternal nutrient restriction during early gestation.External link
Neuroimage (epub 2017), 173:460-471

Agba OB, Lausser L, Huse K, Bergmeier C, Jahn N, Groth M, Bens M, Sahm A,
Gall M, Witte OW, Kestler HA, Schwab M, Platzer M. (2017) Tissue-, sex-, and age-specific DNA methylation of rat glucocorticoid receptor gene promoter and insulin-like growth factor 2 imprinting control region.External link Physiol Genomics, 49(11):690-702

Baumgart M, Barth E, Savino A, Groth M, Koch P, Petzold A, Arisi I, Platzer M, Marz M, Cellerino A. (2017) A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri.External link BMC Genomics, 18(1):693

O'Brien EL, Hess TM, Kornadt AE, Rothermund K, Fung H, Voss P. (2017) Context Influences on the Subjective Experience of Aging: The Impact of Culture and Domains of Functioning.External link Gerontologist, 57(suppl_2):S127-S137

Pallauf K, Duckstein N, Hasler M, Klotz LO, Rimbach G. (2017) Flavonoids as Putative Inducers of the Transcription Factors Nrf2, FoxO, and PPARγExternal link. Oxid Med Cell Longev, 2017:4397340

Busch C, Annamalai B, Abdusalamova K, Reichhart N, Huber C, Lin Y, Jo EAH, Zipfel PF, Skerka C, Wildner G, Diedrichs-Möhring M, Rohrer B, Strauß O. (2017) Anaphylatoxins Activate Ca(2+), Akt/PI3-Kinase, and FOXO1/FoxP3 in the Retinal Pigment Epithelium.External link Front Immunol, 8:703

Feng X, Deistung A, Reichenbach JR. (2018) Quantitative susceptibility mapping (QSM) and R(2)(*) in the human brain at 3T: Evaluation of intra-scanner repeatability. External linkZ Med Phys (epub 2017), 28(1):36-48

Hess TM, O'Brien EL, Voss P, Kornadt AE, Rothermund K, Fung HH, Popham LE.
Context influences on the relationship between views of aging and subjective age: The moderating role of culture and domain of functioning.External link Psychol Aging. 2017 32(5):419-431.

Kuo AH, Li C, Huber HF, Schwab M, Nathanielsz PW, Clarke GD. (2017) Maternal nutrient restriction during pregnancy and lactation leads to impaired right ventricular function in young adult baboons.External link J Physiol, 595(13):4245-4260

Voss P, Kornadt AE, Rothermund K. (2017) Getting what you expect? Future self-views predict the valence of life eventsExternal link. Dev Psychol, 53(3):567-580

Ripa R, Dolfi L, Terrigno M, Pandolfini L, Savino A, Arcucci V, Groth M, Terzibasi Tozzini E, Baumgart M, Cellerino A. (2017) MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging.External link BMC Biol, 15(9)

Frahm C, Srivastava A, Schmidt S, Mueller J, Groth M, Guenther M, Ji Y, Priebe S, Platzer M, Witte OW. (2017) Transcriptional profiling reveals protective mechanisms in brains of long-lived mice.External link Neurobiol Aging, 52:23-31

Micklisch S, Lin Y, Jacob S, Karlstetter M, Dannhausen K, Dasari P, von der Heide M, Dahse HM, Schmölz L, Grassmann F, Alene M, Fauser S, Neumann H, Lorkowski S, Pauly D, Weber BH, Joussen AM, Langmann T, Zipfel PF, Skerka C. (2017) Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator.External link J Neuroinflammation, 14(1):4

Urban N, Tsitsipatis D, Hausig F, Kreuzer K, Erler K, Stein V, Ristow M, Steinbrenner H, Klotz LO. (2017) Non-linear impact of glutathione depletion on C. elegans life span and stress resistance.External link Redox Biol, 11:502-515.

Schäfer N, Grosche A, Reinders J, Hauck SM, Pouw RB, Kuijpers TW, Wouters D,
Ehrenstein B, Enzmann V, Zipfel PF, Skerka C, Pauly D. (2016) Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases.External link
Front Immunol, 7:542

Michelfelder S, Parsons J, Bohlender LL, Hoernstein SNW, Niederkrüger H,
Busch A, Krieghoff N, Koch J, Fode B, Schaaf A, Frischmuth T, Pohl M, Zipfel PF,
Reski R, Decker EL, Häffner K. (2016) Moss-Produced, Glycosylation-Optimized Human Factor H for Therapeutic Application in Complement Disorders.External link J Am Soc Nephrol, 28(5):1462-1474

Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B,
Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL,
Kestler HA, Neri F, von Maltzahn J, Tümpel S, Rudolph KL. (2016) Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.External link Nature, 540(7633):428-432

Wunner C, Reichhart C, Strauss B, Söllner W. (2018) Effects of psychosomatic treatment for the elderly on cognition and quality of life : Naturalistic study at the psychosomatic day care hospital for the elderly in NurembergExternal link. Z Gerontol Geriatr (epub 2016), 51(3):314-321

Ornellas MH, De França Silva M, Solza C, De Lucena Gonçalves SB, Silva De
Almeida L, De Paula Ayres-Silva J, Seixas TL, Bastos EF, Liehr T, Alves G. (2016)
Myelodysplastic syndrome without ring sideroblasts and with Janus kinase 2 gene mutation: An unusual case report.External link Mol Clin Oncol, 5(3):227-230

Freitag J, Berod L, Kamradt T, Sparwasser T. (2016)  Immunometabolism and autoimmunity.External link Immunol Cell Biol, 94(10):925-934

Marthandan S, Menzel U, Priebe S, Groth M, Guthke R, Platzer M, Hemmerich P,
Kaether C, Diekmann S. (2016) Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescenceExternal link. Biol Res, 49(1):34

Platzer M, Englert C. (2016) Nothobranchius furzeri: A Model for Aging Research and MoreExternal link. Trends Genet, 32(9):543-552

Lukjanenko L, Jung MJ, Hegde N, Perruisseau-Carrier C, Migliavacca E, Rozo M,
Karaz S, Jacot G, Schmidt M, Li L, Metairon S, Raymond F, Lee U, Sizzano F,
Wilson DH, Dumont NA, Palini A, Fässler R, Steiner P, Descombes P, Rudnicki MA,
Fan CM, von Maltzahn J, Feige JN, Bentzinger CF. (2016) Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in miceExternal link. Nat Med, 22(8):897-905

Kornadt AE, Hess TM, Voss P, Rothermund K. (2018) Subjective Age Across the Life Span: A Differentiated, Longitudinal ApproachExternal link. J Gerontol B Psychol Sci Soc Sci, 73(5):767-777, Published 2016

Poliezhaieva T, Ermolaeva MA. (2017) DNA damage in protective and adverse inflammatory responses: Friend of foe?External link Mech Ageing Dev (epub 2016), 165(Pt A):47-53

Voss P, Wolff JK, Rothermund K. (2016) Relations between views on ageing and perceived age discrimination: a domain-specific perspectiveExternal link. Eur J Ageing, 14(1):5-15

Li T, Zhou ZW, Ju Z, Wang ZQ. (2016) DNA Damage Response in Hematopoietic Stem Cell AgeingExternal link. Genomics Proteomics Bioinformatics, 14(3):147-154.

Gebauer J, Gentsch C, Mansfeld J, Schmeißer K, Waschina S, Brandes S,
Klimmasch L, Zamboni N, Zarse K, Schuster S, Ristow M, Schäuble S, Kaleta C. (2016) A Genome-Scale Database and Reconstruction of Caenorhabditis elegans Metabolism.External link
Cell Syst, 2(5):312-22

Baumgart M, Priebe S, Groth M, Hartmann N, Menzel U, Pandolfini L, Koch P,
Felder M, Ristow M, Englert C, Guthke R, Platzer M, Cellerino A. (2016) Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.External link Cell Syst, 2(2):122-32

Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL. (2016) Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing.External link Nat Cell Biol, 18(5):480-90. Erratum in: Nat Cell Biol. 2019 21(6):791-792

Hochstenbach R, Nowakowska B, Volleth M, Ummels A, Kutkowska-Kaźmierczak A,
Obersztyn E, Ziemkiewicz K, Gerloff C, Schanze D, Zenker M, Muschke P, Schanze I,
Poot M, Liehr T. (2016) Multiple Small Supernumerary Marker Chromosomes Resulting from Maternal Meiosis I or II ErrorsExternal link. Mol Syndromol, 6(5):210-21

Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM. (2016) Telomere shortening leads to earlier age of onset in ALS mice.External link Aging (Albany NY), 8(2):382-93

Kornadt AE, Meissner F, Rothermund K. (2016) Implicit and Explicit Age Stereotypes for Specific Life Domains Across the Life Span: Distinct Patterns and Age Group Differences.External link Exp Aging Res, 42(2):195-211

Brodoehl S, Klingner C, Witte OW. (2016) Age-dependent modulation of the somatosensory network upon eye closure.External link Behav Brain Res, 298(Pt B):52-6

Schink M, Leipold E, Schirmeyer J, Schönherr R, Hoshi T, Heinemann SH. (2016)
Reactive species modify NaV1.8 channels and affect action potentials in murine dorsal root ganglion neurons.External link Pflugers Arch, 468(1):99-110

Reichwald K, Petzold A, Koch P, Downie BR, Hartmann N, Pietsch S, Baumgart
M, Chalopin D, Felder M, Bens M, Sahm A, Szafranski K, Taudien S, Groth M, Arisi
I, Weise A, Bhatt SS, Sharma V, Kraus JM, Schmid F, Priebe S, Liehr T, Görlach M,
Than ME, Hiller M, Kestler HA, Volff JN, Schartl M, Cellerino A, Englert C,
Platzer M. (2015) Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.External link Cell, 163(6):1527-38

Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J,
Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S,
Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta
C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M. (2015) Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.External link Nat Commun, 6:10043

Kornadt AE, Voss P, Rothermund K. (2017) Age Stereotypes and Self-Views Revisited: Patterns of Internalization and Projection Processes Across the Life SpanExternal link. J Gerontol B Psychol Sci Soc Sci, 72(4):582-592 (Published 2015)

Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R,
Hemmerich P, Diekmann S. (2015)  Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin FibroblastsExternal link. Biomed Res Int, 2015:731938

Perner S, Cronauer MV, Schrader AJ, Klocker H, Culig Z, Baniahmad A. (2015)
Adaptive responses of androgen receptor signaling in castration-resistant prostate cancer.External link Oncotarget, 6(34):35542-55

Kornadt AE, Voss P, Rothermund K. (2015) Hope for the best, prepare for the worst? Future self-views and preparation for age-related changes.External link Psychol Aging, 30(4):967-76

Brodoehl S, Klingner C, Stieglitz K, Witte OW. (2015) The impact of eye closure on somatosensory perception in the elderly.External link Behav Brain Res, 293:89-95

de Rooij SR, van Pelt AM, Ozanne SE, Korver CM, van Daalen SK, Painter RC, Schwab M, Viegas MH, Roseboom TJ. (2015) Prenatal undernutrition and leukocyte telomere length in late adulthood: the Dutch famine birth cohort study.External link Am J Clin Nutr, 102(3):655-60

Sellmann C, Priebs J, Landmann M, Degen C, Engstler AJ, Jin CJ, Gärttner S, Spruss A, Huber O, Bergheim I. (2015) Diets rich in fructose, fat or fructose and fat alter intestinal barrier function and lead to the development of nonalcoholic fatty liver disease over time.External link J Nutr Biochem, 26(11):1183-92

Wendler S, Hartmann N, Hoppe B, Englert C. (2015) Age-dependent decline in fin regenerative capacity in the short-lived fish Nothobranchius furzeri.External link Aging Cell, 14(5):857-66

Adams PD, Jasper H, Rudolph KL. (2015) Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer.External link Cell Stem Cell, 16(6):601-12

Giesen C, Eberhard M, Rothermund K. (2015) Loss of attentional inhibition in older adults--Does it really exist? An experimental dissociation of inhibitory and memory retrieval processes.External link Psychol Aging, 30(2):220-31

Saussele S, Krauss MP, Hehlmann R, Lauseker M, Proetel U, Kalmanti L,
Hanfstein B, Fabarius A, Kraemer D, Berdel WE, Bentz M, Staib P, de Wit M, Wernli
M, Zettl F, Hebart HF, Hahn M, Heymanns J, Schmidt-Wolf I, Schmitz N, Eckart MJ,
Gassmann W, Bartholomäus A, Pezzutto A, Leibundgut EO, Heim D, Krause SW,
Burchert A, Hofmann WK, Hasford J, Hochhaus A, Pfirrmann M, Müller MC. (2015)
Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML study IVExternal link. Blood, 26(1):42-9

Chen Z, Yi W, Morita Y, Wang H, Cong Y, Liu JP, Xiao Z, Rudolph KL, Cheng T,
Ju Z. (2015) Wip1 deficiency impairs haematopoietic stem cell function via p53 andExternal link
mTORC1 pathwaysExternal link. Nat Commun, 6:6808

Hiepe P, Gussew A, Rzanny R, Kurz E, Anders C, Walther M, Scholle HC,
Reichenbach JR. (2015) Age-related structural and functional changes of low backExternal link
muscles.External link Exp Gerontol, 65:23-34

Burkhalter MD, Rudolph KL, Sperka T. (2015) Genome instability of ageing stem cells--Induction and defence mechanismsExternal link. Ageing Res Rev, 23(Pt A):29-36

Genewsky A, Jost I, Busch C, Huber C, Stindl J, Skerka C, Zipfel PF, Rohrer B, Strauß O. (2015) Activation of endogenously expressed ion channels by active complement in the retinal pigment epitheliumExternal link. Pflugers Arch, 467(10):2179-91

Baumgart M, Di Cicco E, Rossi G, Cellerino A, Tozzini ET. (2015) Comparison of captive lifespan, age-associated liver neoplasias and age-dependent gene expression between two annual fish species: Nothobranchius furzeri and Nothobranchius korthauseExternal link. Biogerontology, 16(1):63-9